Adriforant

PF-3893787 is a novel histamine H4 receptor antagonist binding affinity (Ki=2.4 nM) and is also a functional (Ki=1.56 nM) antagonist.

Product Specifications

CAS Number

[943057-12-3]

Product Name Alternative

PF-3893787

UNSPSC

12352005

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Field of Research

Inflammation/Immunology; Endocrinology

Assay Protocol

https://www.medchemexpress.com/adriforant.html

Smiles

NC1=NC(N2C[C@H](NC)CC2)=CC(NCC3CC3)=N1

Molecular Formula

C13H22N6

Molecular Weight

262.35

References & Citations

[1]Mowbray CE, et al. Challenges of drug discovery in novel target space. The discovery and evaluation of PF-3893787: a novel histamine H4 receptor antagonist. Bioorg Med Chem Lett. 2011 Nov 1;21 (21) :6596-602.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

Curated Selection

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