5-Carboxy-X-rhodamin N-succinimidyl ester

5-Carboxy-X-rhodamin N-succinimidyl ester (5-ROX, SE) is a labeling reagent. 5-Carboxy-X-rhodamin N-succinimidyl ester can be used in the preparation of charge-modified dye-labeled Dideoxynucleotide Triphosphates (ddNTP) to "direct-load" DNA sequencing[1].

Product Specifications

CAS Number

[209734-74-7]

Product Name Alternative

5-ROX, SE

UNSPSC

12171500

Hazard Statement

H315-H319-H335

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/5-carboxy-x-rhodamin-n-succinimidyl-ester.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=C(C(C2=CC3=C4N(CCC3)CCCC4=C2[O+]=C56)=C5C=C7CCCN8CCCC6=C87)C(C([O-])=O)=C1)ON9C(CCC9=O)=O

Molecular Formula

C37H33N3O7

Molecular Weight

631.67

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Finn PJ, Sun L, Nampalli S, Xiao H, Nelson JR, Mamone JA, Grossmann G, Flick PK, Fuller CW, Kumar S. Synthesis and application of charge-modified dye-labeled dideoxynucleoside-5'-triphosphates to 'direct-load' DNA sequencing. Nucleic Acids Res. 2002 Jul 1;30 (13) :2877-85.