B7-2/CD86, Cynomolgus/Rhesus Macaque (HEK293, His)

Product Specifications

UNSPSC Description

B7-2/CD86 Protein, Cynomolgus/Rhesus Macaque (HEK293, His), a second CTLA4 ligand expressed on murine B cells, can serve as a costimulatory molecule for T cell activation[1][2].

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/b7-2-protein-rhesus-macaque-hek293-his.html

Purity

95.0

Smiles

YFNETADLPC QFANSQNRSL SELVVFWQNQ ENLVLNEVYL GKEKFDSVHS KYMGRTSFDP ESWTLRLHNL QIKDKGLYQC IIHHKRPTGM IRIHQMNSEL SVLANFSQPE IVPISNITEN MYINLTCSSI HGYPEPEKMS VLLRTKNSTI EYDGVMQKSQ DNVTELYDVS ISLSVSFPDV TSNMTIFCVL ETDKTQLLSS PFSIELEDPQ PPPDHIPHHH HHH

Molecular Weight

40-90 kDa

References & Citations

[1]K S Hathcock, et al. Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function. J Exp Med. 1994 Aug 1;180(2):631-40.|[2]S Tsuyuki, et al. Costimulation through B7-2 (CD86) is required for the induction of a lung mucosal T helper cell 2 (TH2) immune response and altered airway responsiveness. J Exp Med. 1997 May 5;185(9):1671-9.