GSK-269984A

GSK-269984A is a Prostaglandin E2 Receptor 1 (EP1) antagonist with a pIC50 of 7.9.

Product Specifications

CAS Number

[892664-04-9]

UNSPSC

12352005

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Neurological Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/GSK-269984A.html

Purity

99.58

Solubility

DMSO : 7 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

ClC1=CC(F)=C(COC2=CC=C(Cl)C=C2CC3=CC=CC(C(O)=O)=N3)C=C1.[Na]

Molecular Formula

C20H14Cl2FNNaO3

Molecular Weight

429.22

References & Citations

[1]Hall A, et al. Discovery of sodium 6-[ (5-chloro-2-{[ (4-chloro-2-fluorophenyl) methyl]oxy}phenyl) methyl]-2-pyridinecarboxylate (GSK269984A) an EP (1) receptor antagonist for the treatment of inflammatory pain. Bioorg Med Chem Lett. 2009 May 1;19 (9) :2599-603.