GSK-269984A
GSK-269984A is a Prostaglandin E2 Receptor 1 (EP1) antagonist with a pIC50 of 7.9.
Product Specifications
CAS Number
[892664-04-9]
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/GSK-269984A.html
Purity
99.58
Solubility
DMSO : 7 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
ClC1=CC(F)=C(COC2=CC=C(Cl)C=C2CC3=CC=CC(C(O)=O)=N3)C=C1.[Na]
Molecular Formula
C20H14Cl2FNNaO3
Molecular Weight
429.22
References & Citations
[1]Hall A, et al. Discovery of sodium 6-[ (5-chloro-2-{[ (4-chloro-2-fluorophenyl) methyl]oxy}phenyl) methyl]-2-pyridinecarboxylate (GSK269984A) an EP (1) receptor antagonist for the treatment of inflammatory pain. Bioorg Med Chem Lett. 2009 May 1;19 (9) :2599-603.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EP
Available Sizes
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