Sut-8701

Sut-8701 is a Cholecystokinin (HY-P2932) analog that effectively slows the degenerative process of Alzheimer's disease by protecting the integrity of cholinergic neurons in the nucleus basalis[1].

Product Specifications

CAS Number

[123577-73-1]

UNSPSC

12352005

Target

Cholecystokinin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/sut-8701.html

Smiles

O=C(N)[C@H](CC1=CC=CC=C1)NC([C@H](CC(O)=O)NC([C@H](CCCC)NC([C@H](CC2=CNC3=C2C=CC=C3)NC(CNC([C@H](CCCC)NC([C@H](CC4=CC=C(OP(C)(C)=O)C=C4)NC(OC(C)(C)C)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C54H74N9O13P

Molecular Weight

1088.19

References & Citations

[1]Takahashi M, et al. SUT-8701, a cholecystokinin analog, prevents the cholinergic degeneration in the rat cerebral cortex following basal forebrain lesioning[J]. The Japanese Journal of Pharmacology, 1993, 61 (4) : 341-349.