DA 3003-2
DA 3003-2 is a potent and selectively Cdc25 inhibitor. DA 3003-2 shows antiproliferative activity. DA 3003-2 induces cell cycle arrest at the G2/M phase and increases the expression of P-tyr15 Cdc2. DA 3003-2 has the potential for the research of prostate cancer[1].
Product Specifications
CAS Number
[383907-47-9]
Product Name Alternative
NSC663285
UNSPSC
12352005
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/da-3003-2.html
Purity
98.36
Solubility
DMSO : 150 mg/mL (ultrasonic)
Smiles
O=C(C1=C(C2=O)N=CC=C1)C(NCCN3CCOCC3)=C2Cl
Molecular Formula
C15H16ClN3O3
Molecular Weight
321.76
References & Citations
[1]Nemoto K. G2/M accumulation in prostate cancer cell line PC-3 is induced by Cdc25 inhibitor 7-chloro-6- (2-morpholin-4-ylethylamino) quinoline-5, 8-dione (DA 3003-2) . Exp Ther Med. 2010 Jul;1 (4) :647-650.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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