β-Hydroxypropiovanillone

β-Hydroxypropiovanillone, a natural compound, shows significant concentration-dependent inhibitory effects on α-glucosidase with an IC50 of 257.8 μg/mL[1].

Product Specifications

CAS Number

[2196-18-1]

UNSPSC

12352005

Hazard Statement

H302-H312-H332

Target

Glycosidase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/β-hydroxypropiovanillone.html

Purity

97.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OCCC(C1=CC(OC)=C(O)C=C1)=O

Molecular Formula

C10H12O4

Molecular Weight

196.20

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Lv Q , et al. Dihydrochalcone-derived polyphenols from tea crab apple (Malus hupehensis) and their inhibitory effects on α-glucosidase in vitro. Food Funct. 2019;10 (5) :2881-2887.|[2]Higuchi Y, et al. Bacterial Catabolism of β-Hydroxypropiovanillone and β-Hydroxypropiosyringone Produced in the Reductive Cleavage of Arylglycerol-β-Aryl Ether in Lignin. Appl Environ Microbiol. 2018;84 (7) :e02670-17. Published 2018 Mar 19.|[3]Higuchi Y, et al. Discovery of novel enzyme genes involved in the conversion of an arylglycerol-β-aryl ether metabolite and their use in generating a metabolic pathway for lignin valorization. Metab Eng. 2019;55:258-267.