DNA polymerase-IN-1
DNA polymerase-IN-1 (compound 2d) is a DNA polymerase inhibitor (IC50=20.7 μM) with antiproliferative activity against tumor cells[1].
Product Specifications
CAS Number
[809234-33-1]
UNSPSC
12352005
Hazard Statement
H301-H311-H331-H341
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dna-polymerase-in-1.html
Solubility
10 mM in DMSO
Smiles
OC1=C(C(CCl)=CC(O2)=O)C2=CC(O)=C1
Molecular Formula
C10H7ClO4
Molecular Weight
226.61
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P403+P233-P405-P501
References & Citations
[1]Bruna-Haupt EF, et al. Synthesis of Structurally Related Coumarin Derivatives as Antiproliferative Agents. ACS Omega. 2023 Jul 13;8 (29) :26479-26496.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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