Alverine
Product Specifications
UNSPSC Description
Alverine citrate is a 5-HT1A receptor antagonist, with an IC50 of 101 nM.
Target Antigen
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/alverine.html
Smiles
CCN(CCCC1=CC=CC=C1)CCCC2=CC=CC=C2
Molecular Weight
281.44
References & Citations
[1]Coelho, A.M., et al., Rectal antinociceptive properties of alverine citrate are linked to antagonism at the 5-HT1A receptor subtype. J Pharm Pharmacol, 2001. 53(10): p. 1419-26.|[2]Hayase, M., et al., Evolving mechanisms of action of alverine citrate on phasic smooth muscles. Br J Pharmacol, 2007. 152(8): p. 1228-38.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B0500A/Alverine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B0500A/
Clinical Information
Launched
CAS Number
150-59-4
Curated Selection
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