Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

TAT-cyclo-CLLFVY (TFA)

TAT-cyclo-CLLFVY TFA is a cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells. TAT-cyclo-CLLFVY TFA disrupts HIF-1α/HIF-1β protein-protein interaction with an IC50 of 1.3 μM[1].

Product Specifications

UNSPSC

12352209

Target

HIF/HIF Prolyl-Hydroxylase

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tat-cyclo-cllfvy-tfa.html

Solubility

H2O

Smiles

[CGRKKRRQRRRPPQ.cyclo(CLLFVY)(Disulfidebridge:Cys1-Cys1')(TFAsalt)]

Molecular Formula

C111H188N42O24S2.xC2HF3O2

Molecular Weight

2559.08 (free acid)

References & Citations

[1]Elena Miranda, et al. A cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells. J Am Chem Soc. 2013 Jul 17;135 (28) :10418-25.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Anti-BAR | Phosphinothricin N-acetyltransferase (36-50)
AS21 4613 50 µg

Anti-BAR | Phosphinothricin N-acetyltransferase (36-50)

Sign In for Pricing
View Details
CD52 (Epididymis-Specific Protein 5) (CD52/2276R), CF568 conjugate, 0.1mg/mL
BNC682276-100 1x 100 µL

CD52 (Epididymis-Specific Protein 5) (CD52/2276R), CF568 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
E Cadherin (CDH1) (incl. pos. control) Mouse Monoclonal Antibody [Clone ID: 22F8]
AM00010PU-N 100 µg

E Cadherin (CDH1) (incl. pos. control) Mouse Monoclonal Antibody [Clone ID: 22F8]

Sign In for Pricing
View Details
Mouse Fas activation kit by CRISPRa
GA201356 1 Kit

Mouse Fas activation kit by CRISPRa

Sign In for Pricing
View Details
BARX1 (Prognostic Biomarker in Hepatocellular Carcinoma) (BARX1/2759), CF568 conjugate, 0.1mg/mL
BNC682759-100 1x 100 µL

BARX1 (Prognostic Biomarker in Hepatocellular Carcinoma) (BARX1/2759), CF568 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Uncoated Human SIGLEC3 (Sialic Acid Binding Ig Like Lectin 3) ELISA Kit
E-UNEL-H0336-01 5x 96 Tests

Uncoated Human SIGLEC3 (Sialic Acid Binding Ig Like Lectin 3) ELISA Kit

Sign In for Pricing
View Details