DBCO-PEG24-Maleimide

DBCO-PEG24-Maleimide contains a maleimide and a DBCO group. DBCO-PEG24-Maleimide can be used for thiol-containing biomolecule conjugations. DBCO-PEG24-Maleimide can be used in click chemistry with azide-bearing biomolecules[1].

Product Specifications

CAS Number

[2924872-84-2]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

ADC Linker

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dbco-peg24-maleimide.html

Purity

95.28

Solubility

DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1C=CC(=O)N1CCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)NCCC(=O)N2C=3C=CC=CC3C#CC=4C=CC=CC4C2

Molecular Formula

C76H122N4O29

Molecular Weight

1555.81

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Eric Kitas, et al. Targeted linear conjugates comprising polyethyleneimine and polyethylene glycol and polyplexes comprising the same. WO2023079142A3. 2022.