Fluo-3FF AM
Fluo-3FF AM is a low affinity (Kd = 42 μM) fluorescent Ca2+ sensitive indicator (Abs/Em = 462 nm/526 nm) . Fluo-3FF AM is Mg2+ insensitive and relatively photostable. Fluo-3FF AM is an analog of Fluo-3FF AM. Fluo-3FF AM is essentially non-fluorescent, but exhibits a strong fluorescence enhancement upon entry into cells and binding to calcium.[1]
Product Specifications
CAS Number
348079-13-0
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/fluo-3ff-am.html
Solubility
10 mM in DMSO
Smiles
O=C(C)OCOC(CN(CC(OCOC(C)=O)=O)C1=C(OCCOC2=C(C(F)=CC=C2N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)F)C=C(C3=C4C=C(C(C=C4OC5=C3C=C(Cl)C(OCOC(C)=O)=C5)=O)Cl)C=C1)=O
Molecular Formula
C50H46Cl2F2N2O23
Molecular Weight
1151.80
References & Citations
[1]Gordienko DV, et al. Regulation of muscarinic cationic current in myocytes from guinea-pig ileum by intracellular Ca2+ release: a central role of inositol 1,4,5-trisphosphate receptors. Cell Calcium. 2004 Nov;36 (5) :367-86.|[2]Young RC, et al. Focal sarcoplasmic reticulum calcium stores and diffuse inositol 1,4,5-trisphosphate and ryanodine receptors in human myometrium. Cell Calcium. 1999 Jul-Aug;26 (1-2) :69-75.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
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