Efzilonkofusp alfa

Efzilonkofusp alfa is a bispecific Fc fusion protein. Efzilonkofusp alfa is formed by fusing the N-terminal extracellular domain of human CD80 (B7.1) with the Fc fragment of human immunoglobulin G4 (IgG4), and is linked to an interleukin-2 variant (IL-2v) as the C-terminal part. Efzilonkofusp alfa exhibits potential immunostimulatory, immune checkpoint inhibitory, and antitumor activities.

Product Specifications

CAS Number

[2922216-50-8]

Product Name Alternative

GI-102

UNSPSC

12352203

Target

Interleukin Related

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/efzilonkofusp-alfa.html

Smiles

[Efzilonkofuspalfa]

References & Citations

[1]INN Proposed List 131. 11 August 2024.

Shipping Conditions

Room temperature

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Curated Selection

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