GPER activator 1
GPER activator 1 (compound 6-26) is a GPER-selective compound without cytotoxicity. GPER activator 1 exhibits dual inhibition of TNFα- and IL-6-induced inflammation[1].
Product Specifications
CAS Number
2629960-35-4
UNSPSC
12352005
Target
Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/gper-activator-1.html
Smiles
CC1=C(C(C)=C(C(NC(C2=C(C3=C(S2)C=C(F)C=C3)Cl)=O)=N1)C)O
Molecular Formula
C17H14ClFN2O2S
Molecular Weight
364.82
References & Citations
[1]Bhuwan Prasad Awasthi, et al. G Protein-Coupled Estrogen Receptor-Mediated Anti-Inflammatory and Mucosal Healing Activity of a Trimethylpyridinol Analogue in Inflammatory Bowel Disease. J Med Chem.2024 Jul 11;67 (13) :10601-10621.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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