PI3Kγ ligand 1
PI3Kγ ligand 1 is a Ligand for Target Protein for PROTAC (HY-137340) [1].
Product Specifications
CAS Number
[2769753-45-7]
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC; PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pi3kγ-ligand-1.html
Smiles
NCCCN(C1CC1)S(C2=CC=C(C3=CN=C(N)C(C4=CC(CCNC5=O)=C5C=C4)=C3)C=C2)(=O)=O
Molecular Formula
C26H29N5O3S
Molecular Weight
491.61
References & Citations
[1]Donovan KA, et al. Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development. Cell. 2020;183 (6) :1714-1731.e10.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI3Kγ
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