PI3Kγ ligand 1

PI3Kγ ligand 1 is a Ligand for Target Protein for PROTAC (HY-137340) [1].

Product Specifications

CAS Number

[2769753-45-7]

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC; PI3K

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pi3kγ-ligand-1.html

Smiles

NCCCN(C1CC1)S(C2=CC=C(C3=CN=C(N)C(C4=CC(CCNC5=O)=C5C=C4)=C3)C=C2)(=O)=O

Molecular Formula

C26H29N5O3S

Molecular Weight

491.61

References & Citations

[1]Donovan KA, et al. Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development. Cell. 2020;183 (6) :1714-1731.e10.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PI3Kγ

Curated Selection

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