(S) -IB-96212
(S) -IB-96212 (compound 4), an oligomycin derivative, inhibits the MurD2 reaction, but not the MurL reaction. (S) -IB-96212 is a specific inhibitor of the alternative pathway of peptidoglycan biosynthesis. (S) -IB-96212 weakly inhibits the MurD reaction[1].
Product Specifications
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/s-ib-96212.html
Solubility
10 mM in DMSO
Smiles
CC[C@@H](O)[C@H]([C@@H]1O[C@]2([C@@H](C)[C@H](OC(/C=C/[C@H](C)[C@@H](O)[C@@H](C(O)[C@@H]([C@H]3O)O[C@@H]4O[C@H](C)[C@@H](O)CC4)C)=O)[C@H](C)[C@H](CC[C@@H](CC(O)C)/C=C/C=C/C[C@@H](C)[C@H](O)[C@](CCC)(O)C(O)[C@H]3O)O2)CC[C@@H]1C)C
Molecular Formula
C54H94O16
Molecular Weight
999.31
References & Citations
[1]Shuhei Umetsu, et al. Identification of a new oligomycin derivative as a specific inhibitor of the alternative peptidoglycan biosynthetic pathway. J Antibiot (Tokyo) . 2024 Jan 10.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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