Tunicamycin V

Tunicamycin V (Tunicamycin A) is a nucleoside natural product that inhibits bacterial phospho-N-acetylmuramyl-pentapeptide transferase (MraY) with an IC50 of 0.35 μM. Tunicamycin V has antibacterial activties[1][2].

Product Specifications

CAS Number

[66054-36-2]

Product Name Alternative

Tunicamycin A

UNSPSC

12352005

Target

Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/tunicamycin-v.html

Purity

95.0

Solubility

10 mM in DMSO

Smiles

O[C@H]1[C@@H](O)[C@@H](CC[C@H]([C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C=CC(NC3=O)=O)O2)O)O[C@@H](O[C@@H]4[C@H](NC(C)=O)[C@@H](O)[C@H](O)[C@@H](CO)O4)[C@@H]1NC(/C=C/CCCCCCCCCC(C)C)=O

Molecular Formula

C39H64N4O16

Molecular Weight

844.94

References & Citations

[1]Kazuki Yamamoto, et al. Structural requirement of tunicamycin V for MraY inhibition. Bioorg Med Chem. 2019 Apr 15;27 (8) :1714-1719.|[2]Kazuki Yamamoto, et al. Total Synthesis of Tunicamycin V. Org Lett. 2018 Jan 5;20 (1) :256-259.