β-CCB

β-CCB is a ligand for benzodiazepine receptor, which inhibits the binding of [3H]flunitrazepam and ethyl (3-[3H]carboline-3-carboxylate to benzodiazepine receptors, with Ki of 3-4 nM. β-CCB exhibits proconvulsant and anxiogenic effects[1].

Product Specifications

CAS Number

[84454-35-3]

UNSPSC

12352005

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/β-ccb.html

Smiles

O=C(C1=CC2=C(C=N1)NC3=C2C=CC=C3)OCCCC

Molecular Formula

C16H16N2O2

Molecular Weight

268.31

References & Citations

[1]Peña C, et al., Isolation and identification in bovine cerebral cortex of n-butyl beta-carboline-3-carboxylate, a potent benzodiazepine binding inhibitor. Proc Natl Acad Sci U S A. 1986 Jul;83 (13) :4952-6.