β-CCB
Product Specifications
UNSPSC Description
β-CCB is a ligand for benzodiazepine receptor, which inhibits the binding of [3H]flunitrazepam and ethyl (3-[3H]carboline-3-carboxylate to benzodiazepine receptors, with Ki of 3-4 nM. β-CCB exhibits proconvulsant and anxiogenic effects[1].
Target Antigen
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/β-ccb.html
Smiles
O=C(C1=CC2=C(C=N1)NC3=C2C=CC=C3)OCCCC
Molecular Weight
268.31
References & Citations
[1]Peña C, et al., Isolation and identification in bovine cerebral cortex of n-butyl beta-carboline-3-carboxylate, a potent benzodiazepine binding inhibitor. Proc Natl Acad Sci U S A. 1986 Jul;83(13):4952-6.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-100924/β-CCB-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-100924/
Clinical Information
No Development Reported
CAS Number
84454-35-3
Curated Selection
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