Clopamide
Product Specifications
UNSPSC Description
Clopamide is an orally active thiazide-like diuretic agent that inhibits the sodium-coupled chloride cotransporter SLC12A3. Clopamide has the potential for hypertension and cardiac failure research[1][2].
Target Antigen
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/clopamide.html
Purity
99.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NN1[C@H](C)CCC[C@@H]1C)C2=CC=C(Cl)C(S(=O)(N)=O)=C2
Molecular Weight
345.84
References & Citations
[1] J J McNeil, et al. Clopamide: plasma concentrations and diuretic effect in humans. Clin Pharmacol Ther. 1987 Sep;42(3):299-304.|[2]Yoshiteru Noutoshi, et al. Diuretics prime plant immunity in Arabidopsis thaliana. PLoS One. 2012;7(10):e48443.|[3]B Odlind, et al. Renal tubular secretion and effects of chlorothiazide, hydrochlorothiazide and clopamide: a study in the avian kidney. Acta Pharmacol Toxicol (Copenh). 1982 Sep;51(3):187-97.|[4]E Müller-Schweinitzer, et al. Interaction of cyclosporine-A with the renin-angiotensin system in canine veins. Naunyn Schmiedebergs Arch Pharmacol. 1989 Aug;340(2):252-7.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B1477/Clopamide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B1477/Clopamide-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
636-54-4
Available Sizes
Curated Selection
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