Antitumor agent-185

Antitumor agent-185 (compound 3) shows antitumor activity that could effectively reduce the growth of tumors and prolong the survival time of mice in vivo[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Toll-like Receptor (TLR)

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/antitumor-agent-185.html

Smiles

O[C@@H]1C(O[C@@H]([C@H]([C@@H]1O)OC(C[C@@H](CCCCCCCCCCC)OC(CCCCCCCCCCC)=O)=O)COP(O)(O)=O)OC2[C@@H]([C@H]([C@@H]([C@H](O2)COCC3=CN(N=N3)CCO[C@@H]4[C@@H]([C@H]([C@H]([C@H](O4)CO)O)O[C@H]5[C@@H]([C@H]([C@H]([C@H](O5)CO)O)O)O)NC(C)=O)OP(O)(O)=O)OC(C[C@@H](CCCCCCCCCCC)OC(CCCCCCCCCCC)=O)=O)NC(C[C@@H](CCCCCCCCCCC)OC(CCCCCCCCCCC)=O)=O

Molecular Formula

C109H199N5O36P2

Molecular Weight

2217.71

References & Citations

[1]Lingqiang Gao, et al. Design, Synthesis, and Bioactivity Evaluation of a TF-Based Cancer Vaccine Candidate Using Lipid A Mimetics As a Built-In Adjuvant. J Med Chem. 2024 Jun 27;67 (12) :9976-9990.