Temafloxacin

Temafloxacin (TMFX) is an orally active quinolone broad-spectrum antibacterial agent. Temafloxacin is well tolerated in lower respiratory and genitourinary tract infections[1][2].

Product Specifications

CAS Number

[108319-06-8]

Product Name Alternative

TMFX; TA-167 (free acid) ; A-62254 (free acid)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/temafloxacin.html

Purity

99.65

Solubility

DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=CN(C2=CC=C(F)C=C2F)C3=C(C=C(F)C(N4CC(C)NCC4)=C3)C1=O)O

Molecular Formula

C21H18F3N3O3

Molecular Weight

417.38

Precautions

H302, H315, H319, H335

References & Citations

[1]Hardy DJ, et al. Comparative antibacterial activities of temafloxacin hydrochloride (A-62254) and two reference fluoroquinolones. Antimicrob Agents Chemother. 1987 Nov;31 (11) :1768-74. |[2]Pankey GA. Temafloxacin: an overview. Am J Med. 1991 Dec 30;91 (6A) :166S-172S.