Temafloxacin
Temafloxacin (TMFX) is an orally active quinolone broad-spectrum antibacterial agent. Temafloxacin is well tolerated in lower respiratory and genitourinary tract infections[1][2].
Product Specifications
CAS Number
[108319-06-8]
Product Name Alternative
TMFX; TA-167 (free acid) ; A-62254 (free acid)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/temafloxacin.html
Purity
99.65
Solubility
DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CN(C2=CC=C(F)C=C2F)C3=C(C=C(F)C(N4CC(C)NCC4)=C3)C1=O)O
Molecular Formula
C21H18F3N3O3
Molecular Weight
417.38
Precautions
H302, H315, H319, H335
References & Citations
[1]Hardy DJ, et al. Comparative antibacterial activities of temafloxacin hydrochloride (A-62254) and two reference fluoroquinolones. Antimicrob Agents Chemother. 1987 Nov;31 (11) :1768-74. |[2]Pankey GA. Temafloxacin: an overview. Am J Med. 1991 Dec 30;91 (6A) :166S-172S.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Quinolone
Available Sizes
Curated Selection
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