5,7,8-Trimethoxyflavone

5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether), isolated from Andrographis echioides, inhibits NO with an IC50 of 39.1 μM. 5,7,8-Trimethoxyflavone has anti-inflammatory activity[1].

Product Specifications

CAS Number

[23050-38-6]

Product Name Alternative

Norwogonin 5,7,8-trimethyl ether

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

NO Synthase

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/5-7-8-trimethoxyflavone.html

Purity

99.7

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C1C=C(C2=CC=CC=C2)OC3=C(OC)C(OC)=CC(OC)=C13

Molecular Formula

C18H16O5

Molecular Weight

312.32

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]De-Yang Shen, et al. Chemical constituents from Andrographis echioides and their anti-inflammatory activity. Int J Mol Sci. 2012 Dec 27;14 (1) :496-514.