Gly-Phe-β-naphthylamide
Gly-Phe-β-naphthylamide is a substrate of Cathepsin C and belongs to the lysosomal agonist. Gly-Phe-β-naphthylamide can freely pass through the cell membrane and organelle membrane. Gly-Phe-β-naphthylamide will be specifically hydrolyzed by Cathepsin C, ultimately leading to a permeability lysis when it enters the acidic compartment. Gly-Phe-β-naphthylamide can be used to study lysosomal hydrolysis, lysosomal membrane permeability, and the function of cathepsin C[1][2][3].
Product Specifications
CAS Number
21438-66-4
UNSPSC
12352005
Hazard Statement
H351
Target
Cathepsin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/gly-phe-β-naphthylamide.html
Purity
99.92
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C([C@@H](NC(CN)=O)CC1=CC=CC=C1)NC2=CC3=C(C=CC=C3)C=C2
Molecular Formula
C21H21N3O2
Molecular Weight
347.42
Precautions
H351
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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