CooP

CooP is a linear glioblastoma-targeting nonapeptide. CooP binds to the mammary-derived growth inhibitor/fatty acid binding protein 3 (FABP3) in the glioblastoma cells and its associated vasculature. CooP is used for the targeted delivery of chemotherapy and different nanoparticles[1].

Product Specifications

CAS Number

[1192864-27-9]

UNSPSC

12352209

Target

FABP

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/coop.html

Solubility

10 mM in DMSO

Smiles

O=C(NCC(N[C@@H](CC(C)C)C(N[C@@H](CO)C(NCC(N[C@@H](CC(C)C)C(NCC(N[C@@H](C(C)C)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CS)N

Molecular Formula

C32H57N9O11S

Molecular Weight

775.91

References & Citations

[1]Abiodun Ayo, et al. Tumor-Targeting Peptides: The Functional Screen of Glioblastoma Homing Peptides to the Target Protein FABP3 (MDGI) . Cancers (Basel) . 2020 Jul 8;12 (7) :1836.