B-Raf IN 15
B-Raf IN 15 (Compound 7) is a BRAF inhibitor. B-Raf IN 15 inhibits BRAF WT and BRAF V600E with IC50s of 2.0 and 0.8 μM. B-Raf IN 15 can be used for the research of cancer[1].
Product Specifications
CAS Number
[832107-31-0]
UNSPSC
12352005
Target
Raf
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/b-raf-in-15.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=C(C(C2=CSC=C2)NC3=CC=CN=C3)C=CC4=CC=CN=C14
Molecular Formula
C19H15N3OS
Molecular Weight
333.41
References & Citations
[1]Qin J, et al. Identification of a novel family of BRAF (V600E) inhibitors. J Med Chem. 2012 Jun 14;55 (11) :5220-30.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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