Brain-Derived Neurotrophic Factor (BDNF)

<strong>Brain-Derived Neurotrophic Factor (BDNF)</strong>_x000D_ <strong>Catalog number:</strong> B2010332_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 10 ug_x000D_ <strong>pH:</strong> 7.4 upon reconstitution_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure Brain-Derived Neurotrophic Factor (BDNF) expressed in E. coli. This protein acts as a neurotrophin that binds to the tropomyosin-related receptor kinase B (TrkB) receptor and regulates neurodevelopmental processes._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> rHuBDNF/Brain-derived neurotrophic factor; Abrineurin_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Di Carlo P, Punzi G, Ursini G. Brain-derived neurotrophic factor and_x000D_ schizophrenia. Psychiatr Genet. 2019 Oct;29(5):200-210._x000D_ _x000D_ 2: Lima Giacobbo B, Doorduin J, Klein HC, Dierckx RAJO, Bromberg E, de Vries_x000D_ EFJ. Brain-Derived Neurotrophic Factor in Brain Disorders: Focus on_x000D_ Neuroinflammation. Mol Neurobiol. 2019 May;56(5):3295-3312._x000D_ _x000D_ 3: Notaras M, van den Buuse M. Brain-Derived Neurotrophic Factor (BDNF): Novel_x000D_ Insights into Regulation and Genetic Variation. Neuroscientist. 2019_x000D_ Oct;25(5):434-454._x000D_ _x000D_ 4: Zuccato C, Cattaneo E. Brain-derived neurotrophic factor in neurodegenerative_x000D_ diseases. Nat Rev Neurol. 2009 Jun;5(6):311-22._x000D_ _x000D_ 5: Daly C, Ward R, Reynolds AL, Galvin O, Collery RF, Kennedy BN. Brain-Derived_x000D_ Neurotrophic Factor as a Treatment Option for Retinal Degeneration. Adv Exp Med_x000D_ Biol. 2018;1074:465-471._x000D_ _x000D_ 6: Sonal A, Raghavan V. Brain derived neurotrophic factor (BDNF) and suicidal_x000D_ behavior: A review of studies from Asian countries. Asian J Psychiatr. 2018_x000D_ Mar;33:128-132._x000D_ _x000D_ 7: Jablochkova A, Bäckryd E, Kosek E, Mannerkorpi K, Ernberg M, Gerdle B,_x000D_ Ghafouri B. Unaltered low nerve growth factor and high brain-derived_x000D_ neurotrophic factor levels in plasma from patients with fibromyalgia after a_x000D_ 15-week progressive resistance exercise. J Rehabil Med. 2019 Oct_x000D_ 29;51(10):779-787._x000D_ _x000D_ 8: Xu B, Xie X. Neurotrophic factor control of satiety and body weight. Nat Rev_x000D_ Neurosci. 2016 May;17(5):282-92._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/26519901/">9: Björkholm C, Monteggia LM. BDNF - a key transducer of antidepressant effects._x000D_ Neuropharmacology. 2016 Mar;102:72-9. </a>_x000D_ _x000D_ <strong>Products Related to Brain-Derived Neurotrophic Factor (BDNF) </strong> <a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>