Mouse anti Human p19 - ink4d
Product Specifications
Background
The immunogen for the anti-h-p19 was a his-tagged recombinant full length p19 protein recognizing a 19kD protein. The p19ink4d tumor suppressor protein shows no cross reactivity with the closely related inhibitors including p16 ink4a and p15ink4b. p19nk4d is a specific inhibitor of cdk4/cdk6 and is periodically expressed during cell cycle. It is maximally induced as cells enter S phase.
CAS Number
9007-83-4
Synonyms
hp19, p19 ink4d, CDKN2D, Cyclin-dependent kinase 4 inhibitor D
UniProt
P55273 (Human)
Host
Mouse
Species Reactivity
Human
Isotype
IgG1
Clone
DCS-100
Conjugation
Unconjugated
Type
Monoclonal Antibody
Applications
WB, IP, IHC
Field of Research
Cell Cycle
Purification Method
Protein A/G Chromatography
Assay Principle
Applications: Western Blot, Immunoistochemistry, Immunoprecipitation (co-precipitates cdk4/cdk6)
Stability
See expiration date on vial
Concentration
See vial for Concentration
Form
Provided as solution in phosphate buffered saline with 0,08% sodium azide
Precautions
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving Humans or animals.
References & Citations
1) H. Hirai, et. al. (1995) Mol. Cell. Biol. (15) 2672-2681_x000D_
_x000D_
2) JIRINA BARTKOVA, MINNA THULLBERG, PREMYSL SLEZAK, EDGAR JARAMILLO, CARLOS RUBIO, LARS H. THOMASSEN, and JIRI BARTEK. Aberrant Expression of G1-Phase Cell Cycle Regulators in Flat and Exophytic Adenomas of the Human Colon. GASTROENTEROLOGY 2001;120:1680–1688
Shipping Conditions
Room Temperature
Storage Conditions
Product should be stored at -20ºC; Aliquot to avoid freeze/thaw cycles
Functional Analysis
WB
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