[5- (2-Thienyl) -3-isoxazolyl]methanol

[5- (2-Thienyl) -3-isoxazolyl]methanol (Compound D) is an AgrA-DNA binding inhibitor. [5- (2-Thienyl) -3-isoxazolyl]methanol can be used for S.aureus infection research[1].

Product Specifications

CAS Number

[194491-44-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/5-2-thienyl-3-isoxazolyl-methanol.html

Purity

99.88

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OCC1=NOC(C2=CC=CS2)=C1

Molecular Formula

C8H7NO2S

Molecular Weight

181.22

Precautions

H302, H315, H319, H335

References & Citations

[1]Leonard PG, et al. Identification of a hydrophobic cleft in the LytTR domain of AgrA as a locus for small molecule interactions that inhibit DNA binding. Biochemistry. 2012 Dec 18;51 (50) :10035-43.