Trimethadione (Standard)
Trimethadione (Standard) is the analytical standard of Trimethadione. This product is intended for research and analytical applications. Trimethadione (3,5,5, -Trimethyloxazolidine-2,4-dione) is an oxazolidinedione anticonvulsant agent widely used against absences seizures. Trimethadione also is a T-type calcium channel blocker which has antihyperalgesic effects[1][2].
Product Specifications
CAS Number
127-48-0
Product Name Alternative
3,5,5, -Trimethyloxazolidine-2,4-dione (Standard)
UNSPSC
12352005
Target
Calcium Channel; Reference Standards
Type
Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/trimethadione-standard.html
Smiles
O=C(N1C)OC(C)(C)C1=O
Molecular Formula
C6H9NO3
Molecular Weight
143.14
References & Citations
[1]Pastore V, et, al. Synthesis and anticonvulsant activity of bioisosteres of trimethadione, N-derivative-1,2,3-oxathiazolidine-4-one-2,2-dioxides from α-hydroxyamides. Bioorg Med Chem. 2013 Feb 15;21 (4) :841-6.|[2]Barton ME, et, al. The antihyperalgesic effects of the T-type calcium channel blockers ethosuximide, trimethadione, and mibefradil. Eur J Pharmacol. 2005 Oct 3;521 (1-3) :79-85.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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