23-epi-26-Deoxyactein

23-epi-26-Deoxyactein is a natural and orally active anti-obesity and anti-cancer compound[1][2][3].

Product Specifications

CAS Number

[501938-01-8]

Product Name Alternative

27-Deoxyactein

UNSPSC

12352005

Target

PPAR

Type

Natural Products

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/23-epi-26-deoxyactein.html

Purity

99.45

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C[C@]([C@]12C)(C[C@@](O[C@]([C@@](O3)([H])[C@@]43C)(OC4)C5)([H])[C@]2([H])[C@@H]5C)[C@@](CC6)([H])[C@@]7(C[C@H]1OC(C)=O)[C@]([C@]6([H])C8(C)C)(CC[C@@H]8O[C@H](OC[C@H]9O)[C@@H]([C@H]9O)O)C7

Molecular Formula

C37H56O10

Molecular Weight

660.83

References & Citations

[1]Jingjing Yuan, et al. Effects of 23-epi-26-deoxyactein on adipogenesis in 3T3-L1 preadipocytes and diet-induced obesity in C57BL/6 mice. Phytomedicine. 2020 Jun 5;76:153264.|[2]Kwang Sik Suh, et al. Deoxyactein protects pancreatic β-cells against methylglyoxal-induced oxidative cell damage by the upregulation of mitochondrial biogenesis. Int J Mol Med. 2017 Aug;40 (2) :539-548.|[3]Einbond, L.S., et al. Growth inhibitory activity of extracts and purified components of black cohosh on human breast cancer cells. Breast Cancer Res. Treat. 83, 221–231. Breast Cancer Res Treat. 2004 Feb;83 (3) :221-31.|[4]Eun Mi Choi, et al. Deoxyactein Isolated from Cimicifuga racemosa protects osteoblastic MC3T3-E1 cells against antimycin A-induced cytotoxicity. J Appl Toxicol. 2013 Jun;33 (6) :488-94.