Human BMP-4 / BMP2B (improved sequence) Protein, premium grade

Human BMP-4 (improved sequence) Protein, premium grade (BM4-H5118) is expressed from E. coli cells. It is a variant of BMP-4 to suit cell culture applications better.

Product Specifications

Background

Bone Morphogenetic Protein 4 (BMP4) is a member of growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. BMP-4 Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2. BMP-4 can acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction.

Specifications

This protein carries no "tag". The protein has a calculated MW of 13.2 kDa. The protein migrates as 13 kDa±3 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) .

Accession Number

NP_001193.2

Expression Region

Ser 293 - Arg 408

Host

E. coli

Target

BMP-4

Conjugation

Unconjugated

Tag

Native

Source

Human

Stability

-20°C to -70°C for 24 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.