CDCP1 Mouse Monoclonal Antibody [A10F10]
CDCP1 (CUB-domain-containing protein 1) contains three extracellular CUB domains, a transmembrane domain, and two putative cytoplasmic tyrosine phosphorylation sites. Phosphorylation of the gp140 and p80 proteins is mediated by Src family kinases at various tyrosine residues, including Tyr 734. PTP family members mediate the desphosphorylation of CDCP1. The conversion of gp140 to p80 prolongs the phosphorylation state, which may affect signaling in epithelial wounds. CDCP1 acts as a marker for hematopoetic cells and also exhibits high expression in metastatic colon and breast tumors.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
SIMA135, CD318, CDCP1, TRASK
Swiss Prot
Q9H5V8 Human, Q5U462 Mouse
Cellular Locus
Cell membrane. Secreted.
Host
Mouse
Species Reactivity
Human,Mouse
Immunogen
Recombinant protein within Human CDCP1 aa 487-836 / 836.
Isotype
IgG1
Clone
A10F10
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB
Positive Control
SW480 cell lysate, HCT 116 cell lysate, NIH/3T3 cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 93 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
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