CID 5951923

CID 5951923 is a potent inhibitor of Krüppel-like factor 5 (KLF5), with an IC50 of 603 nM. CID 5951923 can inhibit proliferation of cancer cells in vitro[1].

Product Specifications

CAS Number

[749872-43-3]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

KLF

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cid-5951923.html

Purity

98.87

Solubility

DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(OCC(N(C)C(CC1)CS1(=O)=O)=O)/C=C/C2=CC=CC([N+]([O-])=O)=C2

Molecular Formula

C16H18N2O7S

Molecular Weight

382.39

Precautions

H302, H315, H319, H335

References & Citations

[1]Bialkowska AB, et, al. Identification of small-molecule inhibitors of the colorectal cancer oncogene Krüppel-like factor 5 expression by ultrahigh-throughput screening. Mol Cancer Ther. 2011 Nov; 10 (11) : 2043-51.