11-Oxahomoaminopterin
11-Oxahomoaminopterin shows antifolate activity and inhibits Lactobacillus casei DHFFZ with antimicrobial and antitumor activities[1].
Product Specifications
CAS Number
[78520-72-6]
UNSPSC
12352005
Target
Antifolate
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/11-oxahomoaminopterin.html
Smiles
O=C(O)CC[C@@H](C(O)=O)NC(C1=CC=C(OCCC2=NC3=C(N)N=C(N)N=C3N=C2)C=C1)=O
Molecular Formula
C20H21N7O6
Molecular Weight
455.42
References & Citations
[1]Nair MG, et al. Folate analogues altered in the C9-N10 bridge region. 18. Synthesis and antitumor evaluation of 11-oxahomoaminopterin and related compounds. J Med Chem. 1981 Sep;24 (9) :1068-73.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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