11-Oxahomoaminopterin

11-Oxahomoaminopterin shows antifolate activity and inhibits Lactobacillus casei DHFFZ with antimicrobial and antitumor activities[1].

Product Specifications

CAS Number

[78520-72-6]

UNSPSC

12352005

Target

Antifolate

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/11-oxahomoaminopterin.html

Smiles

O=C(O)CC[C@@H](C(O)=O)NC(C1=CC=C(OCCC2=NC3=C(N)N=C(N)N=C3N=C2)C=C1)=O

Molecular Formula

C20H21N7O6

Molecular Weight

455.42

References & Citations

[1]Nair MG, et al. Folate analogues altered in the C9-N10 bridge region. 18. Synthesis and antitumor evaluation of 11-oxahomoaminopterin and related compounds. J Med Chem. 1981 Sep;24 (9) :1068-73.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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