11-Oxahomoaminopterin
Product Specifications
UNSPSC Description
11-Oxahomoaminopterin shows antifolate activity and inhibits Lactobacillus casei DHFFZ with antimicrobial and antitumor activities[1].
Target Antigen
Antifolate
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/11-oxahomoaminopterin.html
Smiles
O=C(O)CC[C@@H](C(O)=O)NC(C1=CC=C(OCCC2=NC3=C(N)N=C(N)N=C3N=C2)C=C1)=O
Molecular Weight
455.42
References & Citations
[1]Nair MG, et al. Folate analogues altered in the C9-N10 bridge region. 18. Synthesis and antitumor evaluation of 11-oxahomoaminopterin and related compounds. J Med Chem. 1981 Sep;24(9):1068-73.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-126878/11-Oxahomoaminopterin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-126878/
Clinical Information
No Development Reported
CAS Number
78520-72-6
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