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Mitoquinone (mesylate)

Mitoquinone mesylate is a TPP-based, mitochondrially targeted antioxidant in order to protect against oxidative damage[1].

Product Specifications

CAS Number

845959-50-4

Product Name Alternative

MitoQ (mesylate) ; MitoQ10 (mesylate)

UNSPSC

12352005

Hazard Statement

H315, H317, H318, H334, H335, H341, H361, H370, H413

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Metabolic Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/Mitoquinone_mesylate.html

Purity

99.09

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C) |Ethanol : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

[O-]S(=O)(C)=O.O=C(C(CCCCCCCCCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)=C4C)C(OC)=C(OC)C4=O

Molecular Formula

C38H47O7PS

Molecular Weight

678.81

Precautions

H315, H317, H318, H334, H335, H341, H361, H370, H413

References & Citations

[1]Mitchell T, et al. The mitochondria-targeted antioxidant mitoquinone protects against cold storage injury of renaltubular cells and rat kidneys. J Pharmacol Exp Ther. 2011 Mar;336 (3) :682-92.|[2]Huang W, et al. Effects of the mitochondria-targeted antioxidant mitoquinone in murine acute pancreatitis. Mediators Inflamm. 2015;2015:901780.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Phase 4

Citation 01

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