SHP389
SHP389 is an allosteric SHP2 inhibitor, with an IC50 of 36 nM for both SHP2 and p-ERK[1].
Product Specifications
CAS Number
2235394-90-6
Product Name Alternative
2-APV; DL-2-Amino-5-phosphonovaleric acid
UNSPSC
12352005
Target
Phosphatase; SHP2
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/shp389.html
Purity
98.03
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C2=C(C3=C(Cl)C(NC4CC4)=NC=C3)NN=C2N=C(N(CC5)CCC65[C@H](N)[C@H](C)OC6)N1C
Molecular Formula
C23H29ClN8O2
Molecular Weight
484.98
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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