Ketorolac-d5
Ketorolac-d5 is a deuterium labeled Ketorolac. Ketorolac is a non-steroidal anti-inflammatory agent, acting as a nonselective COX inhibitor, with IC50s of 20 nM for COX-1 and 120 nM for COX-2[1].
Product Specifications
CAS Number
[1215767-66-0]
UNSPSC
12352005
Hazard Statement
H301
Target
COX
Type
Isotope-Labeled Compounds
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Purity
98.31
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(C1C2=CC=C(C(C3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])=O)N2CC1)O
Molecular Formula
C15H8D5NO3
Molecular Weight
260.30
Precautions
H301
References & Citations
[1]Waterbury LD, et al. Comparison of cyclooxygenase inhibitory activity and ocular anti-inflammatory effects of ketorolac tromethamine and bromfenac sodium. Curr Med Res Opin. 2006 Jun;22 (6) :1133-40.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
COX-1; COX-2
Available Sizes
Curated Selection
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