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Aa1 toxin

Aa1 toxin, a neurotoxic peptide that can be obtained from the venom of Androctonus australis Garzoni, is a specific potassium channel blocker. Aa1 toxin can be used in the study of neurological diseases[1].

Product Specifications

UNSPSC

12352209

Target

Potassium Channel

Type

Peptides

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/aa1-toxin.html

Solubility

10 mM in DMSO

Smiles

O=C([C@@H](N)CCC(N)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H]1CCCCN)=O)=O)C)=O)C)=O)C(C)C)=O)=O)[C@H](CC)C)=O)C(C)C)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CSSC[C@H](NC2=O)C(N[C@H](C(N3[C@H](C(O)=O)CCC3)=O)CC4=CC=C(O)C=C4)=O)=O)C(C)C)=O)CO)=O)C)=O)CSSC[C@H](NC5=O)C(N[C@H]2C(C)C)=O)=O)CO)=O)=O)=O)CCC(N)=O)=O)CSSC[C@H](NC1=O)C(N[C@H](C(N[C@H](C(NCC(N[C@H]5CCCNC(N)=N)=O)=O)CC(N)=O)=O)[C@H](CC)C)=O)=O)CCCCN)=O)CCCCN)=O)CC(N)=O)=O)[C@@H](C)O)=O)CCC(O)=O)=O)CC(N)=O

Molecular Formula

C156H260N54O49S6

Molecular Weight

3868.46

References & Citations

[1]Pisciotta M, et al. Fast K (+) currents from cerebellum granular cells are completely blocked by a peptide purified from Androctonus australis Garzoni scorpion venom. Biochim Biophys Acta. 2000 Sep 29;1468 (1-2) :203-12.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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