Sm4

Sm4 is a SOX18 inhibitor. Sm4 shows SOX18-DNA binding inhibitory activity. Sm4 selectively affects SOX18 transcriptional output in vitro. Sm4 blocks SoxF transcriptional activity in vivo. Sm4 can be used for cancer metastasis and vascular cancers research[1].

Product Specifications

CAS Number

[365542-77-4]

Product Name Alternative

AG-013736 13CD3,SSR-149415,AG-013736-d3

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

HMG Family

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sm4.html

Purity

99.37

Solubility

DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=C(C=CC=C1O)CCC2=CC=C3C=CC=CC3=C2)O

Molecular Formula

C19H16O3

Molecular Weight

292.33

Precautions

H315, H319, H335

References & Citations

[1]Mathias FRANCOIS. Inhibitors of sox18 protein activity for treating angiogenesis- and/or lymphangiogenesis-related diseases. Patent, WO2018112545A1.