Sm4
Sm4 is a SOX18 inhibitor. Sm4 shows SOX18-DNA binding inhibitory activity. Sm4 selectively affects SOX18 transcriptional output in vitro. Sm4 blocks SoxF transcriptional activity in vivo. Sm4 can be used for cancer metastasis and vascular cancers research[1].
Product Specifications
CAS Number
365542-77-4
Product Name Alternative
AG-013736 13CD3,SSR-149415,AG-013736-d3
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
HMG Family
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sm4.html
Purity
99.37
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=C(C=CC=C1O)CCC2=CC=C3C=CC=CC3=C2)O
Molecular Formula
C19H16O3
Molecular Weight
292.33
Precautions
H315, H319, H335
References & Citations
[1]Mathias FRANCOIS. Inhibitors of sox18 protein activity for treating angiogenesis- and/or lymphangiogenesis-related diseases. Patent, WO2018112545A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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