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(S) -Higenamine

(S) -Higenamine ((S) -Norcoclaurine), a S-enantiomer of Higenamine, is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S) -Higenamine is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS) [1].

Product Specifications

CAS Number

22672-77-1

Product Name Alternative

(S) -Norcoclaurine

UNSPSC

12352005

Hazard Statement

H302-H312-H332

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/s-higenamine.html

Solubility

10 mM in DMSO

Smiles

OC1=CC2=C([C@H](CC3=CC=C(O)C=C3)NCC2)C=C1O

Molecular Formula

C16H17NO3

Molecular Weight

271.31

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Minami H, et al. Functional analysis of norcoclaurine synthase in Coptis japonica. J Biol Chem. 2007;282 (9) :6274‐6282.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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