TLR8 agonist 9
TLR8 agonist 9 (Compound II-77) is an agonist for Toll-like receptor 8 (TLR8) with EC50 of 0.25-1 μM. TLR8 agonist 9 is stable in human and murine plasma, induces secretion of cytokines TNFα, with EC50 [1].
Product Specifications
CAS Number
3034750-61-0
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tlr8-agonist-9.html
Smiles
O=C(C=CC1=O)N1CC2OCC(C(N3CCC4=NC=C(NC(C5(CC5)C6=CC=C7C(N=C(N)CC(C(N(CCC)CCO)=O)=C7)=C6)=O)C=C4C3)=O)CO2
Molecular Formula
C38H43N7O8
Molecular Weight
725.79
References & Citations
[1]Zhang W, et al., Benzazepine derivative, conjugate containing same, and use thereof. WO2024067841A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TLR8
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![PE/Cyanine7 Anti-Mouse IgM Antibody[RMM-1]](https://cdn.genprice.uk/products/763/68dd149d061270361e7cf9ca/imageurl/e-ab-f1190uh.webp)
