(S, R, S) -CO-C2-acid
(S, R, S) -CO-C2-acid (VH 032 amide-alkylC2-acid) is a functionalized von-Hippel-Lindau (VHL) protein ligand that can be used in PROTAC research and development. (S, R, S) -CO-C2-acid contains an E3 ligand alkyl ligand for conjugation of target protein ligands[1].
Product Specifications
CAS Number
[2172819-72-4]
Product Name Alternative
VH 032 amide-alkylC2-acid
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-r-s-co-c2-acid.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
OC(CCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)=O)=O)=O
Molecular Formula
C26H34N4O6S
Molecular Weight
530.64
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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