HMCEF
Product Specifications
UNSPSC Description
HMCEF is an orally active P-selectin inhibitor and inhibits P-selectin expression. HMCEF blocks the interaction between P-selectin and natural ligands, such as PSGL-1. HMCEF inhibits thrombosis and inflammation in mice[1].
Target Antigen
P-selectin
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/hmcef.html
Smiles
O=C(O)[C@H](CC1=CC=CC=C1)NCCC2=NC(CO)=CC3=C2NC4=C3C=CC=C4
Molecular Weight
389.45
References & Citations
[1]Wu J, et al. A novel lead of P-selectin inhibitor: Discovery, synthesis, bioassays and action mechanism. Bioorg Med Chem Lett. 2016 Oct 1;26(19):4631-4636.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-122655/HMCEF-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-122655/
Clinical Information
No Development Reported
CAS Number
2002363-68-8
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