HMCEF
HMCEF is an orally active P-selectin inhibitor and inhibits P-selectin expression. HMCEF blocks the interaction between P-selectin and natural ligands, such as PSGL-1. HMCEF inhibits thrombosis and inflammation in mice[1].
Product Specifications
CAS Number
2002363-68-8
UNSPSC
12352005
Target
P-selectin
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/hmcef.html
Smiles
O=C(O)[C@H](CC1=CC=CC=C1)NCCC2=NC(CO)=CC3=C2NC4=C3C=CC=C4
Molecular Formula
C23H23N3O3
Molecular Weight
389.45
References & Citations
[1]Wu J, et al. A novel lead of P-selectin inhibitor: Discovery, synthesis, bioassays and action mechanism. Bioorg Med Chem Lett. 2016 Oct 1;26 (19) :4631-4636.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
RC215640L1V 200 µL
ROR2 (NM_004560) Human Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details 