Favipiravir (sodium)

Favipiravir (T-705) sodium is an inhibitor of viral RNA polymerase (RNA polymerase), which is converted into its active form Favipiravir-ribofuranosyl-5′-triphosphate (RTP) . Favipiravir-RTP inhibits the activity of influenza virus RNA-dependent RNA polymerase (RdRP) with an IC50 of 341 nM[1][2].

Product Specifications

CAS Number

[1366418-99-6]

Product Name Alternative

T-705 (sodium)

UNSPSC

12352005

Target

Bacterial; DNA/RNA Synthesis; Influenza Virus; SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/favipiravir-sodium.html

Smiles

O=C(C1=NC(F)=CN=C1O[Na])N

Molecular Formula

C5H3FN3NaO2

Molecular Weight

179.08

References & Citations

[1]Furuta Y, et al. Favipiravir (T-705), a novel viral RNA polymerase inhibitor. Antiviral Res. 2013 Nov;100 (2) :446-54.|[2]Rocha-Pereira J, et al. Favipiravir (T-705) inhibits in vitro norovirus replication. Biochem Biophys Res Commun. 2012 Aug 10;424 (4) :777-80.