Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Eperisone (hydrochloride)

Eperisone Hydrochloride ((±) -Eperisone hydrochloride) is an orally active antispastic agent with a vasodilator effect, used for the research of muscle stiffness and pain. Eperisone Hydrochloride is a potent and selectively P2X7 receptor antagonist, also shows antagonism for human P2X3. Eperisone Hydrochloride works by relaxing both skeletal muscles and vascularsmooth muscles, demonstrating a variety of effects such as reduction ofmyotonia, improvement of circulationand and suppression of the pain reflex[1][2][3][4][5][6].

Product Specifications

CAS Number

56839-43-1

Product Name Alternative

(±) -Eperisone (hydrochloride)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

P2X Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/eperisone-hydrochloride.html

Purity

99.95

Solubility

DMSO : 31.25 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(CC)C=C1)C(C)CN2CCCCC2.[H]Cl

Molecular Formula

C17H26ClNO

Molecular Weight

295.85

Precautions

H302, H315, H319, H335

References & Citations

[1]Cabitza P, et al. Efficacy and safety of eperisone in patients with low back pain: a double blind randomized study. Eur Rev Med Pharmacol Sci. 2008 Jul-Aug;12 (4) :229-35.|[2]Frandisco Colomer Rusinvol, et al. Effects of Two Diffferent Doses of Eperisone in the Treatment of Acute Low Back Pain. The Journal of Applied Research.|[3]Bavage S, et al. Clinical efficacy and safety of eperisone for low back pain: A systematic literature review. Pharmacol Rep. 2016 Oct;68 (5) :903-12.|[4]Park KH, Lee SC, Yuk JE, Kim SR, Lee JH, Park JW. Eperisone-Induced Anaphylaxis: Pharmacovigilance Data and Results of Allergy Testing. Allergy Asthma Immunol Res. 2019;11 (2) :231-240. |[5]Tanaka KI, et al. Therapeutic effects of eperisone on pulmonary fibrosis via preferential suppression of fibroblast activity. Cell Death Discov. 2022 Feb 8;8 (1) :52.|[6]Okada M, et al. Eperisone Hydrochloride, a Muscle Relaxant, Is a Potent P2X7 Receptor Antagonist. Chem Pharm Bull (Tokyo) . 2024;72 (3) :345-348.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

1,9-Dichlorononane
TRC-D434625-2.5G 2.5 g

1,9-Dichlorononane

Sign In for Pricing
View Details
N-Nitroso Dabigatran Etexilate Mesylate
TRC-N405550-50MG 50 mg

N-Nitroso Dabigatran Etexilate Mesylate

Sign In for Pricing
View Details
a-Ethyl 2C-D Hydrochloride
TRC-E594260-5MG 5 mg

a-Ethyl 2C-D Hydrochloride

Sign In for Pricing
View Details
Human Herpes Virus 8 (HHV8) (LN53), Biotin conjugate, 0.1mg/mL
BNCB1746-100 1x 100 µL

Human Herpes Virus 8 (HHV8) (LN53), Biotin conjugate, 0.1mg/mL

Sign In for Pricing
View Details
(R)-(-)-2-Amino-1-butanol
TRC-A602205-500MG 500 mg

(R)-(-)-2-Amino-1-butanol

Sign In for Pricing
View Details
Heptaminol
TRC-H281170-250MG 250 mg

Heptaminol

Sign In for Pricing
View Details