PPARα/γ agonist 4
PPARα/γ agonist 4 (Compound (S) -7) is an orally active dual potent agonist of PPARα and PPARγ, with EC50 values of 0.061 μM and 1.42 μM respectively. PPARα/γ agonist 4 acts through an insulin-independent mechanism and exhibits mitochondrial pyruvate carrier inhibition and anti-diabetic properties. PPARα/γ agonist 4 is expected to be used in research for dyslipidemic type 2 diabetes[1].
Product Specifications
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/pparα-γ-agonist-4-1.html
Smiles
O=C(O)[C@H](CC1=CC=CC=C1)OC2=CC=C(C=C2)C3=C4C(C=CC=C4)=CC=C3
Molecular Formula
C25H20O3
Molecular Weight
368.42
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PPARα; PPARγ
Frequently Asked Questions
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