Myrtucommulone A
Product Specifications
CAS Number
54247-21-1
UNSPSC Description
Myrtucommulone A is a non-prenylated acylphloroglucinol that can be isolated from Myrtus communis (myrtle). Myrtucommulone A interacts with the HSP60 chaperone and inhibits HSP60 chaperone activity. Myrtucommulone A decreases the expression of LRP130, LONP[1][2].
Target Antigen
HSP
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/myrtucommulone-a.html
Smiles
CC(C)[C@@H](C(C(C(C)(C1=O)C)=O)=C(C1(C)C)O)C(C(O)=C2C(C(C)C)=O)=C(C([C@H](C(C(C(C)(C3=O)C)=O)=C(C3(C)C)O)C(C)C)=C2O)O
Molecular Weight
668.81
References & Citations
[1]Wiechmann K, et al. Mitochondrial Chaperonin HSP60 Is the Apoptosis-Related Target for Myrtucommulone. Cell Chem Biol. 2017 May 18;24(5):614-623.e6.|[2]Hans M, et al. Stereoisomeric Composition of Natural Myrtucommulone A. J Nat Prod. 2015 Oct 23;78(10):2381-9.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
Frequently Asked Questions
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