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Myrtucommulone A

Product Specifications

CAS Number

54247-21-1

UNSPSC Description

Myrtucommulone A is a non-prenylated acylphloroglucinol that can be isolated from Myrtus communis (myrtle). Myrtucommulone A interacts with the HSP60 chaperone and inhibits HSP60 chaperone activity. Myrtucommulone A decreases the expression of LRP130, LONP[1][2].

Target Antigen

HSP

Type

Natural Products

Related Pathways

Cell Cycle/DNA Damage;Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/myrtucommulone-a.html

Smiles

CC(C)[C@@H](C(C(C(C)(C1=O)C)=O)=C(C1(C)C)O)C(C(O)=C2C(C(C)C)=O)=C(C([C@H](C(C(C(C)(C3=O)C)=O)=C(C3(C)C)O)C(C)C)=C2O)O

Molecular Weight

668.81

References & Citations

[1]Wiechmann K, et al. Mitochondrial Chaperonin HSP60 Is the Apoptosis-Related Target for Myrtucommulone. Cell Chem Biol. 2017 May 18;24(5):614-623.e6.|[2]Hans M, et al. Stereoisomeric Composition of Natural Myrtucommulone A. J Nat Prod. 2015 Oct 23;78(10):2381-9.

Shipping Conditions

Room temperature

Clinical Information

No Development Reported

Frequently Asked Questions

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