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Catechin (hydrate)

Catechin hydrate inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.

Product Specifications

CAS Number

[88191-48-4]

Product Name Alternative

(+) -Catechin (hydrate) ; Cianidanol (hydrate) ; Catechuic acid (hydrate)

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

COX

Type

Natural Products

Related Pathways

Immunology/Inflammation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/catechin-hydrate.html

Smiles

O[C@@H]1[C@@H](C2=CC(O)=C(O)C=C2)OC3=CC(O)=CC(O)=C3C1.O

Molecular Formula

C15H16O7

Molecular Weight

308.28

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Waffo-Téguo P, et al. Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures. Nutr Cancer. 2001;40 (2) :173-9.|[2]Alshatwi AA. Catechin hydrate suppresses MCF-7 proliferation through TP53/Caspase-mediated apoptosis. J Exp Clin Cancer Res. 2010 Dec 17;29:167.|[3]Cheruku SP, et al. Catechin ameliorates doxorubicin-induced neuronal cytotoxicity in in vitro and episodic memory deficit in in vivo in Wistar rats. Cytotechnology. 2018 Feb;70 (1) :245-259.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

Launched

Isoform

COX-1

Curated Selection

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